A letter from the Great Golden Tooth makes the peaceful life ripple again. Hu Bayi, Wang Fatzi and Miss Yang embarked on an adventure again in order to find out the truth about the Miao drug Gu and the mysterious person behind the scenes. After returning to Nanjing, they were wanted by the state, and while fleeing, they entered the ancient tomb of Yangshan and went deep into Fuxian in Miaojiang to uncover a series of thrilling secrets.